Editorial building illustration for LEGO Pokémon Mewtwo's Lab Break SMART Play set

Editorial illustration; see LEGO for current product photography.

Evidence-based review · Updated September 10, 2026

LEGO Pokémon Mewtwo's Lab Break 72163 Review

This 605-piece set recreates Mewtwo breaking out of its lab chamber. The physical mechanism and articulated figure work on their own; responsive SMART Play lights and sounds require a SMART Brick from another set.

Age10+
Pieces605
LEGO price checked$69.99
SMART Tags1
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What children build

The main model is Mewtwo's lab tank. A front dial triggers the breakout action, and the set includes a highly posable Mewtwo plus a Master Ball. LEGO lists the Mewtwo figure at more than 7.5 inches tall.

SMART Play requirement

Mewtwo includes one SMART Tag, but the set does not include a SMART Brick. Electronic reactions therefore require hardware from an All-in-One set such as Training House with Pikachu 72164 or Charizard vs. Jolteon 72167.

Screen and app use

The physical build and SMART Play interaction are designed around hands-on play rather than a child-facing screen. The optional SMART Assist app is used by adults for support and Brick updates. We do not classify this as a generative AI toy.

Best fit

72163 makes the most sense for a Mewtwo fan age 10+ who either already owns a SMART Brick or values the large figure and lab scene as a standalone build. Buyers starting the SMART Play ecosystem from zero should account for the cost of an All-in-One set.

Strengths

  • Large articulated Mewtwo
  • Mechanical breakout action
  • Strong display value
  • Currently available at LEGO US

Tradeoffs

  • No SMART Brick included
  • Only one SMART Tag
  • Age 10+ fit
  • Total interactive system cost exceeds $69.99

Verdict

This is a compelling character-driven expansion, not the best starter. Buy it for Mewtwo and the lab scene first; treat SMART Play interactivity as an added benefit if the family already owns a Brick.

Compare LEGO Pokémon SMART Play sets →

Sources